Blog
Ebola Viru-highest-level viruses in the world Jul 01, 2022

Whats the Ebola Virus ?

Ebola virus it is a very rare virus discovered in 1976 in the Ebola River region of southern Sudan and Congo (DRC) (formerly known as Zaire). Ebola hemorrhagic fever (EBHF) is the most deadly viral hemorrhagic fever in the world today. It is very similar to Marburg virus, which is also in the Fibroviridae family, including nausea, vomiting, diarrhea, skin color change, body aches, internal bleeding, external bleeding, fever, etc. Mortality rates vary from 50% to 90%, [1] mainly due to stroke, myocardial infarction, hypovolemic shock, or multiple organ failure.

Ebola virus belongs to the Filoviridae family, with a length of 970 nanometers, a long filamentous, single-stranded negative-strand RNA virus with 18959 bases and a molecular weight of 4.17×10⁶. There is an envelope outside, the diameter of the virus particle is about 80 nanometers, and the size is 100 nanometers × (300-1500) nanometers. The virus with strong infectivity is generally about 665-805 nanometers long, with branched, U-shaped, 6-shaped or ring-shaped, branched. shape is more common. It has a capsule and has 8-10 nanometer long fibers on the surface. The pure virus particle is composed of a helical ribonucleocapsid complex, containing negative-strand linear RNA molecules and 4 virion structural proteins. Long, oddly-shaped virion-related structures can be branched or coiled, up to 10 microns long. Ebola strains from Congo (DRC), Ivory Coast and Sudan differ in their antigenic and biological characteristics.

 

HOW the Ebola Virus Spreads ?

Ebola virus is mainly transmitted through the blood, saliva, sweat and secretions of patients

Laboratory tests often show lymphopenia, severe thrombocytopenia, and elevated transaminases (AST > ALT), and sometimes elevated blood amylase. Diagnosis is by ELISA for specific IgG antibodies (the presence of IgM antibodies indicates infection); ELISA for antigens in blood, serum, or tissue homogenates; IFA for viral antigens in hepatocytes by monoclonal antibodies; or by cell culture or guinea pigs Inoculate isolated virus. Viruses can sometimes be observed in liver sections with electron microscopy. Detection of antibodies with IFA often leads to misdiagnosis, especially when conducting serological investigations of previous infections. Laboratory research is very risky and should only be conducted where safeguards are in place to prevent infection among workers and the community

How to detect  Ebola Virus ?

Ebola virus is a highly dangerous pathogen, and isolation and identification of the virus must be carried out in specialized laboratory facilities. In African epidemic areas, diagnosis is mainly made by detecting Ebola virus-specific IgM and IgG antibodies and checking viral antigens or nucleic acids.

and we aslo supply the Ebola rapid test kit as auxiliary detection,high accuracy and specific was recognized by African Countries.