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Monkeypox Virus IgG/IgM Antibody Test Sep 01, 2022

INTENDED USE

Monkeypox Virus IgG/IgM Antibody Test is intended for the In Vitro qualitative detection MPV IgG/IgM antibody in human serum or plasma. It is only used as an auxiliary detection indicator for Monkeypox Virus (MPV) infection. This product can be used in a clinical setting/health-care setting/laboratory setting.

SUMMARY

Monkeypox is a viral zoonosis (a virus transmitted to humans from animals) with symptoms very similar to those seen in the past in smallpox patients, although it is clinically less severe. With the eradication of smallpox in 1980 and subsequent cessation of smallpox vaccination, monkeypox has emerged as the most important orthopoxvirus for public health. Monkeypox primarily occurs in Central and West Africa, often in proximity to tropical rainforests and has been increasingly appearing in urban areas. Animal hosts include a range of rodents and non-human primates. Monkeypox virus is an enveloped double-stranded DNA virus that belongs to the Orthopoxvirus genus of the Poxviridae family. After a person is infected with MPV for the first time, the body's immune system will carry out immune defense against the virus and produce specific antibodies, and IgM antibodies will be produced in the body of acute infection 3~7, which mainly exist in the acute infection period. A few days later, IgG antibodies began to appear and increase, and the presence in the body was longer than that of IgM antibodies, with better affinity, suggesting the presence of previous infection.

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