Why do they test for calprotectin? Sep 14, 2022
A calprotectin test may be ordered when a person has symptoms that suggest inflammation of the digestive system and when a healthcare practitioner wants to distinguish between IBD and a non-inflammatory bowel condition. Signs and symptoms of IBD will vary from person to person and over time.
Having a raised calprotectin level generally means you have active inflammation in your body. This is generally associated with inflammatory bowel diseases (IBD) such as Crohn's disease or ulcerative colitis. The higher the level of faecal calprotectin the more inflammation present in your intestines.
As a general rule, high levels of calprotectin indicate bacterial or parasitic infections, colorectal cancer or certain diseases that cause intestinal inflammation, such as ulcerative colitis and Crohn's disease. In those latter cases, the higher the calprotectin, the more severe the inflammation.

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